6-Methyl-2,7-diphenyl-1,4-diazepan-5-one
نویسندگان
چکیده
The title compound, C(18)H(20)N(2)O, crystallizes with two mol-ecules in the asymmetric unit. The seven-membered ring in both mol-ecules adopts a distorted chair conformation. The dihedral angles between the phenyl rings are 43.2 (1) and 54.7 (1)° in the two mol-ecules. The crystal packing features N-H⋯O and weak N-H⋯π and C-H⋯π inter-actions.
منابع مشابه
Synthesis, crystal structures and docking studies of 2,7-diphenyl-1,4-diazepan-5-one derivatives
BACKGROUND 1,4-Diazepine derivatives are the seven membered, nitrogen containing heterocyclic ring systems possessing a wide range of therapeutic applications. 1,4-Diazepines attracted the attention of chemists and druggists due to their biological and medicinal properties, such as antimicrobial, anti-HIV and anticancer activities. Herein, we report the preparation, crystal structure determined...
متن کاملc-3,t-3-Dimethyl-r-2,c-7-diphenyl-1,4-diazepan-5-one
In the title compound, C(19)H(22)N(2)O, the diazepine ring adopts a distorted chair conformation. One of the N-H groups forms an inter-molecular N-H⋯O hydrogen bond generating an R(2) (2)(8) graph-set motif. The other N-H group does not form a hydrogen bond.
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The synthesis of 3-methyl-1,4-diphenyl-7-thioxo-4,6,8,9-tetrahydropyrazolo[5,4-b] pyrimidino[5,4-e]pyridine-5-one (6) was achieved by two different one-pot multi-component synthesis (one-pot three-component and one-pot four component synthesis). Mono and dialkylation of 6 under different conditions gave compounds 7-11. The hydrazine 12 produced from reaction of 9 with N₂H₄ was subjected to reac...
متن کاملSynthesis, Characterization and Antioxidant Studies of Quinazolin Derivatives
3-((4-(dimethylamino)benzylidene)amino)-2-methylquinazolin-4(3H)-one (3), 3-((4hydroxybenzylidene)amino)-2-methylquinazolin-4(3H)-one (4), 2-methyl-3-(pyrrolidin-2-ylideneamino) quinazolin-4(3H)-one (5) and 3,3'-((1,4-phenylenebis(methanylylidene)) bis(azanylylidene))bis(2methylquinazolin-4(3H)-one) (6) derived from 3-amino-2-methylquinazolin-4(3H)-one have been synthesized and characterized by...
متن کاملExpeditious, four-component synthesis of 1,4-dihydropyrano[2,3-c]pyrazole derivatives catalyzed by trichloroacetic acid or ceric sulfate.
Two efficient and convenient procedures for the synthesis of 6-amino-3-methyl-1,4-diphenyl-1,4-dihydropyrano[2,3c]pyrazole-5-carbonitrile derivatives based on four-component reaction involving ethyl acetoacetate, phenylhydrazine, malononitrile, and various aromatic aldehydes using trichloroacetic acid or ceric sulfate as heterogeneous catalysts in excellent yields and short reaction times have ...
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عنوان ژورنال:
دوره 65 شماره
صفحات -
تاریخ انتشار 2009